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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLNS1A
All Species:
23.94
Human Site:
Y147
Identified Species:
37.62
UniProt:
P54105
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54105
NP_001284.1
237
26215
Y147
E
D
E
D
S
D
D
Y
D
G
E
E
Y
D
V
Chimpanzee
Pan troglodytes
XP_001175048
222
24569
P137
C
E
C
Q
A
L
H
P
D
P
E
D
E
D
S
Rhesus Macaque
Macaca mulatta
XP_001088333
203
22330
Y118
D
D
Y
D
G
E
E
Y
D
V
E
A
H
E
Q
Dog
Lupus familis
XP_535567
226
24585
Y141
D
D
Y
D
G
E
E
Y
D
V
E
A
H
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q61189
236
26003
Y146
E
D
E
D
S
D
D
Y
D
G
E
E
Y
D
V
Rat
Rattus norvegicus
Q04753
236
26074
Y146
E
D
E
D
S
D
D
Y
D
G
E
E
Y
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519221
278
30242
E157
D
D
S
D
D
D
Y
E
G
G
E
Y
D
V
E
Chicken
Gallus gallus
XP_423253
238
26615
Y148
D
E
D
S
D
N
D
Y
E
G
D
E
Y
D
V
Frog
Xenopus laevis
P54106
241
26428
Y151
D
A
D
S
D
D
D
Y
E
G
D
E
Y
D
V
Zebra Danio
Brachydanio rerio
NP_571499
249
27316
E160
D
D
D
Y
E
G
E
E
Y
D
V
E
E
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611237
215
23724
F130
E
D
A
V
D
E
Q
F
G
E
V
T
E
C
W
Honey Bee
Apis mellifera
XP_624081
207
23224
N122
R
F
A
P
D
N
T
N
N
L
E
A
M
F
Q
Nematode Worm
Caenorhab. elegans
NP_001021287
205
22895
S120
F
V
P
D
D
K
D
S
L
S
Q
I
Y
H
Q
Sea Urchin
Strong. purpuratus
XP_001194575
165
18108
R80
G
N
E
V
R
E
I
R
L
V
P
Q
D
K
T
Poplar Tree
Populus trichocarpa
XP_002318279
231
25740
C146
L
F
Q
V
F
C
E
C
A
E
L
N
P
E
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.2
85.6
82.2
N.A.
90.3
90.3
N.A.
40.6
82.3
72.1
68.2
N.A.
20.2
40
29.9
24.4
Protein Similarity:
100
93.2
85.6
85.2
N.A.
94.9
94.9
N.A.
53.2
90.3
82.5
80.3
N.A.
37.5
56.5
45.5
40.9
P-Site Identity:
100
20
33.3
33.3
N.A.
100
100
N.A.
33.3
46.6
53.3
13.3
N.A.
13.3
6.6
20
6.6
P-Site Similarity:
100
40
66.6
66.6
N.A.
100
100
N.A.
40
86.6
80
33.3
N.A.
26.6
20
26.6
26.6
Percent
Protein Identity:
25.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
48.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
14
0
7
0
0
0
7
0
0
20
0
7
0
% A
% Cys:
7
0
7
0
0
7
0
7
0
0
0
0
0
7
0
% C
% Asp:
40
54
20
47
40
34
40
0
40
7
14
7
14
40
0
% D
% Glu:
27
14
27
0
7
27
27
14
14
14
54
40
20
20
14
% E
% Phe:
7
14
0
0
7
0
0
7
0
0
0
0
0
7
0
% F
% Gly:
7
0
0
0
14
7
0
0
14
40
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
14
7
0
% H
% Ile:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
0
% I
% Lys:
0
0
0
0
0
7
0
0
0
0
0
0
0
7
0
% K
% Leu:
7
0
0
0
0
7
0
0
14
7
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
7
0
0
0
14
0
7
7
0
0
7
0
0
0
% N
% Pro:
0
0
7
7
0
0
0
7
0
7
7
0
7
0
7
% P
% Gln:
0
0
7
7
0
0
7
0
0
0
7
7
0
0
27
% Q
% Arg:
7
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% R
% Ser:
0
0
7
14
20
0
0
7
0
7
0
0
0
0
7
% S
% Thr:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
7
% T
% Val:
0
7
0
20
0
0
0
0
0
20
14
0
0
7
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
0
0
14
7
0
0
7
47
7
0
0
7
40
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _